Innovative Methodology MOUSE PHENOME PROJECT New replicable anxiety-related measures of wall vs. center behavior of mice in the open field
نویسندگان
چکیده
Dina Lipkind, Anat Sakov, Neri Kafkafi, Gregory I. Elmer, Yoav Benjamini, and Ilan Golani Department of Zoology, George S. Wise Faculty of Life Sciences, and Department of Statistics and Operations Research, The Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv, Israel 69978; and Maryland Psychiatric Research Center, Department of Psychiatry, School of Medicine, University of Maryland, Baltimore, Maryland 21228
منابع مشابه
New replicable anxiety-related measures of wall vs center behavior of mice in the open field.
Anxiety is a widely studied psychiatric disorder and is thought to be a complex and multidimensional phenomenon. Sensitive behavioral discrimination of animal models of anxiety is crucial for the elucidation of the behavioral components of anxiety and the physiological processes that mediate them. Commonly used behavior paradigms of anxiety usually include only a few automatically collected mea...
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The Effect of Dexamethasone on Anxiety Related Behavior in Mice A.A. Vafaei PhD , H. Miladi-Gorgi MSc , A.A. Taherian MD2, A. Rashidy-Pour PhD Received: 08/05/06 Sent for Revision: 05/10/06 Received Revised Manuscript: 12/11/06 Accepted: 14/12/06 Background and Objective: Previous studies have suggested that activation of the glucocorticoid receptors may have a modulatory effect on fear and anx...
متن کاملEstimating wall guidance and attraction in mouse free locomotor behavior.
In this study, we estimate the influence exerted by the wall of the Open Field on the trajectory of the mouse. The wall exerts two types of influence on the mouse's path: one of guidance and one of attraction. The guiding influence is expressed by the tendency of mice to progress in parallel to the wall. This tendency wanes with increasing distance from the wall but is observed at large distanc...
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تاریخ انتشار 2004